Incredible Gemfibrozil And Simvastatin References. Web insulin sensitivity decreased by 27% and 28% during gemfibrozil and simvastatin treatment, respectively. If a fibrate is to be used in combination with a statin, then fenofibrate is generally the fibrate of choice.

A higher risk of serious adverse events results from combining these drugs,. Using gemfibrozil with simvastatin or other. Web insulin sensitivity decreased by 27% and 28% during gemfibrozil and simvastatin treatment, respectively.